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Actors Mindy Kaling from left, Oprah Winfrey and Reese Witherspoon pose for a portrait at The W Hotel in Los Angeles to promote their film, "A Wrinkle in Time." (Photo by [Rebecca Cabage/Invision/AP)

Actors Mindy Kaling from left, Oprah Winfrey and Reese Witherspoon pose for a portrait at The W Hotel in Los Angeles to promote their film, "A Wrinkle in Time." (Photo by [Rebecca Cabage/Invision/AP)

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Q&A: Oprah plays life coach to 'Wrinkle in Time' co-stars

"A Wrinkle in Time" director Ava DuVernay insists she didn't consciously assemble three of the entertainment industry's most successful and entrepreneurial women to play the celestial, all-knowing "Mrs." characters in Oprah Winfrey, Reese Witherspoon and Mindy Kaling.